PGA & HA: Synergistic Enhancement, Taura zvakanaka kune Kunamira, Moisturizing uye Antioxidant Duet

#Introduction

Sodium polyglutamate (PGA)i polymer inonyungudika nemvura inogadzirwa nemicrobial fermentation.Inoshandiswa zvakanyanya mukuchengetwa kwegandazvigadzirwa uyezvizoronekuda kweiyo yakanakisa moisturizing zvimiro uye multifunctional zvimiro.Ichi chinyorwa chichasuma kunobva, chimiro chemakemikari, maitiro uye kushandiswa kwesodium polyglutamatemune zvigadzirwa zvekuchengetedza ganda zvakadzama.

#Mabviro uye Chemical Mamiriro

Sodium polyglutamateyakatanga kuwanikwa mu natto, chikafu chechinyakare cheJapan.Sirika ine viscous yakanyanya mu natto ndeyePGA.Ichi chinhu chine polymerized kubva kune yakasikwa uye inoshatisa glutamic acid uye inogadzirwa nekuvirisa kweBacillus subtilis.Bacillus subtilis inozivikanwa pasi rese yakachengeteka microbial additive (GRAS) dhizaini, yakangotorwa uye yakachengeteka kumuviri wemunhu.

Iyo yakakosha chimiro chePGAinoumbwa ne5000-10000 glutamic acid mamorekuru akaitwa polymerized kuburikidzaγ-amide zvisungo.Iyo molecule ine nhamba huru yemapoka epolar akadai sehydroxyl uye carboxyl mapoka, ayo anogona kuumba hydrogen zvisungo mukati uye pakati pemamorekuru, nokudaro achisunga yakawanda yemvura uye zvakanyanya kunatsiridza maitiro ayo ekunyorovesa.

# Zvimiro uye Mhedzisiro

1. **Excellent moisturizing performance**: PGA inogona kutora uye kukiya yakawanda yemvura, zvakanyanya kuvandudza hydration yeganda.Kana yakashandiswa nesodium hyaluronate (HA), inogona kurebesa nguva yekunyorova yeHA, kuderedza kunamatira kwayo, uye kuita kuti ganda rinzwe rakasikwa uye rakatsetseka.

2. **Antioxidant basa**: PGA ine antioxidant chiitiko, inogona kuchenesa mahara radicals, uye kudzivirira ganda kubva mukukuvadzwa kweiyo oxidative.Zvidzidzo zvakaratidza kuti PGA ine molecular huremu hwe1.4 miriyoni Da inoita zvishoma zvirinani pane PGA ine molecular uremu hwe1 miriyoni Da mukutsvaira DPPH yemahara radicals.

3. **Wedzera izvo zvemukati moisturizing factor (NMF) muganda**: PGA inogona kusimudzira chizvarwa cheNMF muganda, kusimudzira kugona kunyorova kweganda, uye kuwana mhedzisiro yekudya kwakadzika.

4. **Kuchena uye anti-kuchembera**: PGA inogona kudzora zvinyoro-nyoro basa re tyrosinase, kunonoka kuumbwa kwemavara, uye panguva imwechete inovandudza kugadzikana kweHA muganda, kuwedzera HA zvinyorwa, uye kuzadzisa mhedzisiro yekuchena uye kurwisa-kukwegura.

# Molecular Weight uye Mashandisiro

Zvinoenderana nehuremu hwemamorekuru, PGA inogona kukamurwa kuita marudzi matatu: yakakwira molecular uremu, yepakati molecular uremu uye yakaderera molecular uremu, imwe neimwe iine akasiyana maitiro uye mashandisiro:

- **PGA-HMW (yakakwira molecular uremu,> 700kDa)**: kunyorovesa kwenguva refu, kuumba firimu rinonyorovesa pamusoro peganda, kunyanya kuvandudza maitiro ekunyorova.

- **PGA-LMW (yepakati molecular uremu, 70-150kDa)**: kunyorova uye kuchena, kuvandudza kupenya kweganda uye elasticity.

- **PGA-Oligo (yakaderera molecular uremu, <10kDa)**: kudya kwakadzika, kunosvika zvakananga kubhesi, kusimudzira chizvarwa cheNMF uye kunwa kwezvinovaka muviri.

# Mazano uye Kushandisa Mazano

PGA inokodzera kunyorovesa, anti-kuchembera uye chena zvigadzirwa, ine yakakurudzirwa kusangana kwe0.1% kusvika 1%.Anti-ionic emulsifiers inofanirwa kushandiswa zvakanyanya sezvinobvira mufomula yekugonesa mhedzisiro yePGA.

# Mhedziso

Seyakasikwa, yakachengeteka uye inoshanda biopolymer,sodium polyglutamate (PGA)inoratidza kugona kukuru kwekushandisa muzvigadzirwa zvekuchengetedza ganda uye zvizoro.Iyo yakanakisa moisturizing zvimiro, antioxidant chiitiko uye akawanda mabhenefiti kuhutano hweganda inoita kuti ive chinhu chakakosha muzvigadzirwa zvemazuva ano zvekuchengetedza ganda.Nekudzika kwekutsvaga uye kufambira mberi kwehunyanzvi hwekushandisa,PGAinotarisirwa kuita basa rakakosha mune mamwe minda uye kuunza humwe hutsva nebudiriro kune tekinoroji yekuchengetedza ganda.